Sentence examples for negative experiments from inspiring English sources

And although it may be possible for you to publish and gain professional mileage from negative experiments, it is the breakthrough positive results that will gain you the most recognition.

As we did not observe any alteration in the BBB, we add our data to the negative experiments that the BBB does not change its permeability during migraine attacks.

The possibility of supersolid behavior in 4He was predicted many years ago, but negative experiments in the 1970's removed motivation for further experimental efforts to explore the possibility until the work of Goodkind's group renewed attention.

On the one hand, Collins argues that the decision between these conflicting experimental results could not be made on epistemological or methodological grounds—he claims that the six negative experiments could not legitimately be regarded as replications[7] and hence become less impressive.

To corroborate the dominant negative experiments, we analyzed the effects on spine morphology of two different TRIM3 RNAi constructs (TRIM3/264, directed against part of the coding sequence, and TRIM3/2756, targeted against the 3' untranslated region).

In the 66 negative experiments, it was unclear whether ET had failed to produce an effect (may be no ET receptor was present in the recorded patch of membrane or the pore/channel activation occurred during the process of sealing of the patch pipette to the plasma membrane of granule cell).

We propose this approach to be superior to experiments testing for lack of cross-reactivity among possible related enzymes, which is a challenging negative experiment.

The inability of lectins to block CT binding is a negative experiment, and is weak evidence at best that sialic acids are not involved.

We suspect however that more valuable lessons can be learned from this negative experiment in addition to the difficulty of conducting large clinical trials in general practice.

The reactions were stopped by immediately boiling the samples for 5 min. In protease-negative experiments, 30 µl of inactivated GI fluid was used (inactivated samples were prepared by heating chick intestinal tract fluid at 95°C for 15 min followed by cooling down on ice).

For dominant-negative experiments, RASMC were transfected with a 2 5 complex of dominant-negative PXR (PXR-DN) or empty vector pcDNA 3.1 V5 His plasmid DNA and LipofectamineTM 2000 (Invitrogen, Paisley, UK) as previously described for 24 h prior to treatment.