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Synthetic repressors have been developed to treat dominant negative diseases and to silence oncogenes.
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Remissions were ongoing in five of six patients achieving CR at a median follow-up of 26 months (range 5 34); the other progressed with CD19 negative disease.
Postoperative S100A6 concentrations were similar in patients with different T stages (A), nodal positive vs. negative disease (B), UICC-stadiums (C), well-differentiated vs. undifferentiated tumors (D).
And while prevention trumps having to fight off triple negative disease, researchers honed in on two successful ways to do it this year.
There is also an increased proportion of smear negative disease [6].
There are clear changes between latent infection and active disease and differences between smear positive and smear negative disease.
HER2 overexpression often occurs with estrogen receptor (ER) negative disease, making these tumors resistant to hormonal therapies [2].
Chemotherapy, mainly 5-fluorouracil, epirubicin, cyclophosphamide (FEC), was recommended to all women with node-positive disease or node-negative, hormone receptor negative disease.
All patients had either node positive or high-risk node negative disease.
No patient received induction chemotherapy; all had lymph node negative disease.
This report reiterates the difference in biology between hormone receptor (HR) positive and negative disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com