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When the models use one-lagged explanatory variables, there is thus an offset between the positive demonstration effect and negative differentiation effect, causing an insignificant decline in the regression coefficient.
In total, only 98 out of 1,222 sera (8.0%) demonstrated discrepant results regarding positive and negative differentiation by visual and automated interpretation.
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These data indicate that DMP1 plays negative roles in differentiation of Nestin+ cells and bone formation.
Furthermore, they were found to be negative for classical differentiation markers such as neurofilament heavy chain (ectoderm), renin (mesoderm), and amylase (endoderm).
It has therefore been clearly established that high avidity interactions of the developing T cells with thymic stromal cells can lead to two quite distinct outcomes: negative selection and differentiation of Treg.
In addition to the negative effect of differentiation, our results show that migrant pupils perform better in destination countries that have a higher student-teacher ratio, also with control for the average score of the native pupils.
These data are somewhat unexpected, as usually a positive effect on proliferation is accompanied by a negative effect on differentiation and the opposite.
Next we compared tumor-initiating potential between SSEA1 positive and negative cells following differentiation of Pten−/− ESCs for four days in RA.
The tumours did not have the histological appearance of trichofolliculomas and were negative for terminal differentiation markers of all three epidermal lineages: several hair keratins (HF), involucrin (IFE) and Oil Red (SG) (data not shown).
There was no signal overlap between fresh RCC and negative control, making differentiation straightforward.
KRT19 has been identified in epidermal stem/progenitor cell population with a role in negative regulation of differentiation [ 52].
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