ER, PR and HER2 status was determined by mRNA expression as positive or negative, as defined in the original METABRIC publication (Curtis et al., 2012).
The percentage of tumour cells with EMP2 immunoexpression was recorded for each specimen and loss of EMP2 expression (negative) was defined in cases with staining ≤5% tumour cells (see the Statistical analysis section).
It must be noted that the triple-negative subtype defined in our study contains both array-defined basal-like tumor and unclassified subtypes, since we have not performed immunohistochemical staining for HER1 and cytokeratin 5/6 [ 12].
A non-positive (negative, uniformly negative) subspace is defined in a similar way.
Negative control is defined in part 121 of this title.
Its (m,n th entry is defined as (mathbb {E}left [frac {partial ^{2}}{partial theta _{n} partial theta _{m}} ell left (mathbf {h}, boldsymbol {sigma }^{mathbf {2}}right)right ]), where ℓ(h,σ 2 ) is the negative log-likelihood defined in (7).
Negative correlations were defined in the same manner but in the opposite direction.
Let ( Ω, F, P ) be a given complete probability space and τ k 's be non-negative random variables defined in ( Ω, F, P ), k = 1, 2, … .
Patients with Xpert-positive or Xpert-negative tuberculosis were defined in 2 ways, initially using the first sputum sample result and then using both sputum sample results.
This leads to sort of re-ethicising the idea of responsibility, but responsibilisation here is predominantly defined in negative terms: moral agency focuses on avoiding negative consequences, which becomes the only (or the most) morally acceptable objective of action.
