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Included in the control group were 15 BSE negative animals, confirmed by post-mortem histology.
From the remaining probes the average ratio of MCF positive vs MCV negative animals was computed.
All negative animals were devoid of PK resistant PrPSc in the kidney.
Tick marks on the curves represent the time point at which HIV-1 negative animals were censored from the analysis.
In contrast, wild type KP9 sequences strongly dominated in the brain of Mane-A*10 negative animals (Table 2).
Our previous evaluation was also based on a gold standard approach using PCR confirmed MTBC infected and lesion negative animals as the positive and negative population, respectively [25].
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Seven animals with latent TB and four Mtb-negative animals were infected with SIV, with the four Mtb-negative animals designated as the SIV-only control group.
Four probable bacteriological culture false-negative animals were identified by Discriminant Function Analysis.
Co-infected animals had fewer T cells in involved lungs than SIV-negative animals with active TB despite similar T cell numbers in draining lymph nodes.
Of these, sixteen and fourteen SIV-negative animals were intravaginally inoculated with SHIVsf162P3 and SIVmac251 respectively as previously described and blood from another 6 uninfected animals were added to controls [14].
To our surprise, the Mamu-B*17-negative animals in that study also had expanding populations of CD8+ T cells that targeted Vif and Nef (Figs. 1 and 2).
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