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The purposes of this review are, first, to examine various methods of vascularising tissue-engineered grafts, and, second, to compare the role of angiogenesis in tissue engineering, where stimulation of angiogenesis is paramount, with pathological states, such as tumour growth, where angiogenesis needs to be inhibited.
If the CEA/CEACAM6-mediated disruption of tissue architecture is to persist, this process needs to be inhibited.
Thus, RNA-interference (RNAi) appears to be a remarkable tool with potential applications for use in clinical practice, for the treatment of diseases caused by a defective gene, which needs to be inhibited.
However, the aPKC activity needs to be inhibited at other neurites to subsequently achieve the axon dendrite polarity.
This result suggested that the T regulatory system first needs to be inhibited and then, macrophage stimulators should be given.
To obtain a stronger Th1 response, giving only the Th1 response stimulator is not enough; the T regulatory system needs to be inhibited.
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These data would suggest that, in order to target Apc-deficient cells, the crypt progenitor phenotype would need to be inhibited and sole inhibition of the Lgr5/stem cell phenotype would not be sufficient.
During focused attention however, responses to targets at the non-instructed level need to be inhibited, i.e. inter-hemispheric inhibition is necessary.
What's more, there was no longer any need to be inhibited.
These circuits reveal a set of kinases that are most predictive of drug sensitivity and depict combinations of kinases that need to be inhibited to prevent tumor growth.
A mathematical model could provide the means to systematically identify the set of nodes which need to be inhibited rather than activated to achieve desired cell type transition.
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