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We conclude that a large portion of the apex needs to be affected by severe changes in calcium regulation or contractile function to result in apical ballooning, and smooth linear variation from apex to base is unlikely to result in the typical ventricular shape observed in this syndrome.
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The question is really becoming how many more generations need to be affected before we listen to the evidence and change our current course?" the report says.
"You need to be affected by it directly to start to take notice but it's important to note that fracking has found itself to the top of the local political agenda because people have mentioned it when they've been canvassed," she said.
It also seems important that both Atg4A and Atg4B need to be affected if endogenous regulatory or exogenous intervening mechanisms are to be exerted at this level of autophagy function.
Disturbance of consciousness (i.e. reduced clarity of awareness of the environment) with reduced ability to focus, sustain and shift attention; to fulfil this criterion the levels of both consciousness and attention need to be affected.
These data strongly suggest that more than one variant (of different genes) will need to be affected in these cases to reach the threshold for a fully penetrant phenotype.
They need a beginning, a middle, and an end and the person telling the story needs to change, to be affected by what happened.
Both bills double the amount of wealth you would need to have to be affected by the estate tax, and the House plan phases it out entirely over time.
Usher's is a "recessive" disease - you need two copies of the gene to be affected.
In fact, you need not be in a wheelchair to be affected by this problem.
Also, when it is highly probable that a pixel is on the edge, it needs to be less affected by the neighboring pixels.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com