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Considering the results of killed control and the positive correlation between the Mn2+ release rates and protein concentrations, we speculate the bioreduction process may be an enzymatic reaction, which needs further demonstration.
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25 31 This treatment dramatically changed the gut microbiota and then the metabolic phenotype, suggesting that it could be causal, although demonstration of the causality needs further evaluation in germ-free mice.
Therefore the conclusion that engrailed is activated in a non-autonomous manner needs further evidence, perhaps with higher quality anti-En staining and a demonstration that Ptc expression is suppressed in these cells.
This needs further attention".
"His statement needs further investigation".
This issue needs further exploration.
This needs further explanation.
This needs further investigation.
However, this needs further experimentation.
The reason needs further studied.
This hypothesis needs further investigation.
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