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Third, there are increased needs for representative data to describe the epidemic and related resource needs for care and treatment at the local and national levels.
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In order to improve large-scale carbon mapping efforts, our findings stress the need for representative sampling strategies, along with subsequent improvement of allometric equations, which together reflect the variability within the observed Savanna vegetation gradient.
However, the wide variation of BTs concentrations in the study area, i.e., over a very small geographic scale, illustrates the need for representative hierarchical and composite sampling designs that are compatible with the multiscalar temporal and spatial variability common to most marine systems.
The need for a new surveillance approach to understand the clinical outcomes and behaviors of people in care for HIV evolved from the new challenges for monitoring clinical outcomes in the HAART era, the impact of the epidemic on an increasing number of areas in the US, and the need for representative data to describe the epidemic and related resource utilization and needs.
In pre-clinical research aiming at the identification of novel treatment targets, the need for representative cell lines and model systems is high, but availability is scarce.
Despite the demonstrable success of single cell analysis the technical requirements needed for representative amplification of single cells and the downstream analysis remain a considerable barrier for widespread implementation in the research community.
Selection of sites in these CEM programmes was predominantly influenced by a need for representative geographic distribution, although malaria prevalence and willingness of HCPs to participate were also seen as important factors.
The need for representative ground data obtained using a robust spatial sampling strategy is highlighted and the example of how this was achieved in MODIRISK, a project aiming at mapping mosquito species and biodiversity patterns in Belgium, is given.
Because a heritability estimate is a population-specific snapshot, and most heritability estimates were based on samples of convenience [ 36], there emerged a need for representative epidemiological twin samples.
However, the need for representative samples and the notion of 'generalizability' is different in qualitative research compared to quantitative research, where the focus of the former is not to measure, explain, or predict [ 23, 24].
With the establishment of docetaxel as effective treatment for HRPC, the need for representative test systems to compare combination strategies became relevant and information regarding docetaxel responses of the various cell lines and xenograft models has become an additional selection parameter.
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