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Localization of our model drug, sulforhodamine B in the microneedle tip by either casting a highly concentrated polymer solution as the needle matrix or incorporating an air bubble at the base of the microneedle achieved approximately 80% delivery within 10 min compared to 20% delivery achieved by the microneedles encapsulating nonlocalized drug.
An EDS spectrum showed the chemical compositions of the attachments were 40.36% C, 14.60% O, 4.18% Si, 8.33% Cr, 30.00% Fe and 2.53% Ni, and 23.14% C, 11.15% O, 4.56% Si, 12.39% Cr, 46.34% Fe and 2.42% Ni for needles S6 and S8, respectively, where C, O and Si were from the composition of the gel, and Cr, Fe and Ni were from the needle matrix.
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The amino acid sequences of the HBHA from M. tuberculosis and M. bovis were searched with the Entrez Protein search engine and then the sequences were aligned with the Needle program, EBLOSUM62-Matrix (EMBOSS, [12]).
The needle-shaped β′-Ge precipitates are coherent with the Al matrix along the needle direction which is parallel to a 〈0 0 1〉Al direction, as well as one direction in the cross-section plane that is parallel to a 〈1 0 0〉Al direction.
Sewing prepreg tape can be more difficult because the inherent tackiness of the uncured resin matrix impedes the needle action.
Irregular aggregates of radiating stilpnomelane needles extended into the silica matrix.
The top part of the coating consists of Mg2Si dendrites, Al12Mg17 matrix and bright needle-like Al3Mg2 phase.
We studied the photocatalytic degradation of pollutant (Rhodamine 6G) using ZnO nano-needles embedded in white cement matrix under ultraviolet irradiation (UV) along with enhanced hydrophobic nature and the antimicrobial property of the cement.
Another important feature is that glass-ceramic microstructures can be designed to enhance fracture toughness, as in the case of the A/W glass-ceramic, composed of an apatite matrix reinforced by needle-like wollastonite crystals [ 9, 10].
Using his wife's knitting needles, Dart flaked away the rock matrix, and a tiny face was revealed.
The radioisotopes, with half-lives ranging from ~10 60 days [ 76] are delivered to the prostate as seeds through a matrix of narrow diameter needles inserted transperineally.
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