The ability to analyze gene expression using a standard reporter is an important and critically needed tool to study gene regulation and design genetic screens for C. difficile and other anaerobic clostridia.
CpArray15K is the first microarray chip developed for C. parvum, which provides the Cryptosporidium research community a needed tool to study the parasite transcriptome and functional genomics.
CpArray15K is the first microarray chip developed for C. parvum, which provides the Cryptosporidium research community a needed tool to study parasite transcriptome and functional genomics.
Conceivably, the synthetic advances discussed above will enable the generation of antibodies recognizing mono-ADP-ribosylated proteins, and will thus provide a much needed tool to study ADP-ribosylation.
Zebrafish models of CDG will provide much-needed tools to study CDG pathology because development of mice with hypomorphic alleles is costly and time consuming, and the mice generated thus far have failed to adequately replicate the abnormal gene expression, developmental abnormalities, protein hypoglycosylation and loss of LLOs associated with the human disease.
Recent interest in testing whether the success of antigen-specific immunotherapy (ASIT) for autoimmune diseases in mice can be translated to humans has highlighted the need for better tools to study and understand human autoimmunity.
This and other evidence has highlighted the complexity of the transcriptome and the need for better tools to study it [ 23, 49].
This justifies the need for pan and zoom tools to study a particular region of interest.
21– 23 Therefore, the researchers need to select the appropriate definition as well as tools to study FS.
We expect that the release of this Gene Index will provide much needed tools for the study of CPG construction and evolution, sexual selection and speciation, and the molecular evolution of arthropods.
This technology provides researchers and clinicians with the tools needed to study 3-dimensional changes in craniofacial anatomy associated with the growth process and clinical care.
