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Depending on the treatment needed, some patients can already be cared for entirely on an ambulatory basis or at least receive sufficient treatment from office-based doctors to avoid hospitalization.
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Dental and orthodontic services for optimal dental form and function may also be needed, and some patients may require psychological intervention for the development of healthy self-esteem.
More extensive surgery may be needed for some patients, if indicated by their preoperative evaluation.
§A shorter interval may be needed in some patients, particularly those with status asthmaticus.
Advanced neurophysiological procedures including invasive EEG recordings may be needed in some patients [ 36, 43, 77], as discussed further below.
While anti-VEGF treatment provides good efficacy in many patients, frequent injections may be needed and some patients may be partial responders or nonresponders [ 12].
However, further drug development and coformulations of other antiretroviral medications, particularly with a once-daily administration, are needed because some patients cannot tolerate or are resistant to Atripla.
Longer-acting analogs (detemir, glargine) may not have time-activity profiles that are as long, flat, and stable as needed for some patients.
Long-term follow-up is needed because some patients whose clinical presentation may suggest a secondary FSGS may progress to full NS.
This class effect highlights the necessity to monitor bone loss and fracture risk in all patients receiving AI therapy, and suggests that pharmacotherapy may be needed in some patients to prevent bone loss and reduce fracture risk.
Also, the model is limited to a maximum end-expired concentration of 8% - higher concentrations might be needed in some patients, but this comes at a risk of irritating the airway.
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