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The present work was performed with the aim to test the bidirectionality hypothesis and results confirmed the needed predictions to fulfill it.
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Depending on the number of ligands that needed prediction and time available, a choice for one method can be made.
If needed, prediction coverage can be raised to 77% (934/1218) by including non-reciprocal matches, but PPV then decreases to 82% (769/934) PPV.
The models are mainly needed for predictions outside the parameter space.
From the needs of organisms in their adaptation to the exigencies of their environment develop the conceptual tools needed for prediction of future conditions.
Computational models of MFC are needed for prediction and optimization of the MFC performance.
So, a more rational approach is needed for prediction of siRNA off-targets that needs understanding of the miRNA target recognition procedure.
As ARMAsel itself functions based on prediction error evaluations, we might not even need further prediction error evaluations.
Clearly no single model or platform can provide all the predictions needed.
Selection of additional traits may be needed for better predictions of overall performance of restoration plantings.
We also felt that they were not needed to make predictions at the global scale.
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CEO of Professional Science Editing for Scientists @ prosciediting.com