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Targeted therapy to the heterogeneous group of TNBC is needed in combination with chemotherapy.
Here, initiative from the relevant clinical professional societies and patients groups may be needed in combination with simplification and improvements of regulatory requirements, to enable timely implementation of highly beneficial developments to improve medicine and patient care.
This emphasizes that targeted therapies, potentially specific for each subtype, are needed in combination with improved methods for early detection.
Alternatively, other genes outside the APA locus may be needed in combination with arcelin for resistance to be expressed.
Multi-faceted, patient-tailored methods of treatment are needed, in combination with improvement of adherence, i.e. disease-management programmes such as collaborative care [ 24, 26- 29].
Interestingly, a lower concentration of 5-FU was needed in combination with curcumin to inhibit the proliferation and viability of HCT116R cells.
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(The notion that evolutionary change occurs in response to need in combination with an internal striving toward greater perfection is a common misconception that is often attributed to Lamarck; see Kampourakis and Zogza 2007 for criticism of this practice).
Thus, these patients may lack assistance from close relatives or friends when needed, which in combination with lower social functioning, may prevent them from getting optimal hospital care, when needed (it is worth mentioning that all patients were recruited from a well functioning welfare community with equal access to support and help).
Such DCV will need testing in combination with other approaches such as cytokine therapy and chemotherapy.
Public sector organisations are confronted with growing health and social care needs in combination with severe resource constraints, prompting interest in innovative responses to such challenges.
It will site well-established brands recognised for introducing more innovative approaches to product innovation driven by user need in combination with more responsible textile selection.
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