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New stent designs are needed for this indication.
The novel aspect of the proposed trial is to investigate non-inferiority of placebo against adequate antibiotic treatment in addition to well-defined standardized treatment of moderate AE-COPD in order to show that antibiotics are not needed for this indication.
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However as SAE does not always guarantee haemostasis in cases of severe PPH; the indications of transfer if needed for this treatment should be carefully discussed in light of the patient's haemodynamic status to minimise the risks.
2 Such statements are also needed for supplemental indication approvals.
Acetaminophen was permitted to be taken as needed for appropriate indications.
When treatment is needed for approved indications, clinicians should be aware that AP drugs should cautiously be used, especially among patients at high risk of PE, for example by using minimal effective doses and avoiding polypharmacy, as we observed that dose and use of two or more AP drugs substantially increased the risk.
RRT in the course of AKI was always initiated when needed for the following indications: pulmonary edema, oliguria (defined as urine output <0.5 ml/kg body weight per hour for >6 hours), metabolic acidosis or hyperkalemia not responding to conventional treatment and uremia defined as urea nitrogen of >100 mg/dl.
They also recommend that: "When permission from key decision-makers associated with each cluster is needed for assigning interventions, some indication should be provided as to who these decision-makers are and how they were identified.
However, because of the potential seriousness of complications associated with ECMO, and because of the skills needed for management of such treatment, experts recommend that patients requiring VV ECMO or VA ECMO be managed in centers with all the means needed to define the indications for ECMO and to implement and manage it in safe conditions.
The ocular safety and visual function evaluation was an additional component based on newly emerging ocular safety signals with the use of sildenafil on an as needed basis for the indication of erectile dysfunction.
While temporary jobs are not the sustained employment the economy needs for recovery, they are another indication that companies are needing to restaff.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com