Sentence examples for needed for differentiation from inspiring English sources
In the present model, the CD4SP/CD8SP thymocyte ratio is controlled by the Tc parameter, which defines the average number of successive Tint interactions of a given DP cell with the same epithelial cell needed for differentiation into CD4SP thymocytes or, otherwise in the CD8SP cell subset.
On the other hand, we show that blocking Ret expression and activation by siRNA hampers as well the process of differentiation thus indicating that in LAN-5 and SH-SY5Y cells the concurrent activity of both receptors is needed for differentiation.
In this situation, C6 cell even increases the production of selective proteins such as GFAP and c-fos and c-jun [ 29] that may be needed for differentiation.
In our future experiments, it is planned to use the TSA-based differentiation protocol in view of its simplicity and the short duration needed for differentiation.
Consistently, the inverse relationship between these miRNAs and the cell differentiation status suggests that their downregulation is needed for differentiation triggering.
To address this need, we focused initially on occupancy by TAL1, since this TF plays multiple key roles in hematopoiesis and is needed for differentiation of erythroid progenitor cells into maturing erythroblasts [ 30].
Not only is there need for differentiation in indicator achievement goals depending on the needs of the patient group, questions may also be asked about the relevance and the completeness of the QOF indicators.
In early pluripotent mesenchymal stem cells, Wnt/β-catenin signaling needs to be precisely regulated to facilitate the differentiation of osteoblasts; by contrast, β-catenin is not needed for chondrocyte differentiation.
Our previous work has provided strong evidence that the transcription factor SOX9 is completely needed for chondrogenic differentiation and cartilage formation acting as a "master switch" in this differentiation.
In effusion cytology, adjuvant techniques are often needed for the differentiation of reactive proliferating mesothelial cells and malignant cells.
The genes for two other "master" transcription factors, MyoD [34] and Myogenin [35] which are not expressed in chondrocytes but are needed for myoblast differentiation, did not have SOX9 interaction sites consistent with the high degree of specificity of the role of SOX9 in the chromatin of chondrocytes.
