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Although many data have demonstrated that α2M* could bind with cell surface GRP78 and stimulate the signaling pathways downstream of cell surface expression of GRP78, we still need to preclude the possibility that α2M* binds with other cell surface protein and facilitates c-Src phosphorylation.
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This should be contrasted with the idea of admissibility of a trading strategy, which is a mathematical artefact needed to preclude unrealistic arbitrage opportunities (like doubling strategies), which may be present within a stochastic model when continuous trading is allowed.
Explanations could include sufficient supply and demand for transactional sex within populations to preclude the need to go outside one's community, or the populations may be uncomfortable in undertaking transactional sex arrangements with persons from an "unknown" community.
People with straighter or slicker hair may need to use what is called "aqua wax" or a protein hair gel to help the style last, and to preclude the need for extra tension during styling.
Adequate centralized funding of public schools, making a city school sufficiently adequate to preclude the need for choice, is much more sensible.
In the present and coming marketplace, suits made to measure through the precision of body scanning and produced by digital printers, engineered to resist staining and creasing or to preclude the need for wasteful and damaging dry cleaning are either familiar items on the shop rail or at prototype stage.
When asked about Mr. Bloomberg's criticisms, Errol Cockfield, a spokesman for Mr. Paterson, said the governor was involved in discussions with the state's Indian nations, those recognized by the state or the federal government, "to preclude the need for more endless litigation".
We hypothesized that preoperative axillary ultrasound (AUS) with fine-needle aspiration is sufficiently sensitive to detect worrisome macrometastasis to preclude the need for frozen-section pathology of SLNs.
In addition, the ratio of piston stroke to diameter should not exceed a value of one to minimize friction and leakage losses, but should be large enough to preclude the need for an oversized motor.
"I think anytime we can find a way to preclude the need to use new resources, we're better off on many levels," he says.
Importantly, neither metformin nor other non-insulin therapies are likely to preclude the need for insulin to maintain glycemic control in some patients.
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