Sentence examples for need to be down from inspiring English sources

We don't need to be down.

She didn't need to be down Ashford Designer Outlet Centre buying shoes.

"I need to be down there, be with the guys," he told the trainers.

"I'm obviously not a sinkerball pitcher, but I need to be down and on the outside corner to be successful.

"I don't understand why black people feel this undying need to be down with white people all the time," he said last month in a video posted by TMZ.

In future, people will no longer need to be down to their last £23,000 before they get help – the help starts at £123,000, as recommended in the Dilnot report.

Overexpression of Pu.1 impairs the emergence of IgG1-positive cells in vitro, its expression need to be down-regulated to permit class-switched B-cells to undergo differentiation to plasma cells [24], [25].

The prominent down-regulation of genes at the early stages of the differentiation process was in agreement with previous studies showing that the levels of transcriptional repressors, such as Id2 and Id4 [48]–[50], Hes5 [52], [52] and Tcf7l2 [21], [53], [53] need to be down-regulated in order to allow myelin gene expression to proceed.

This diversity makes a potential therapeutic immunomodulation very complex, as some cell types would need to be down-regulated while others need to be stimulated.

Therefore, those mRNAs that need to be down-regulated at a very high speed require regulatory mechanisms that decrease their stability.

It is able to bind to co-repressors such as TLE and directly repress genes that need to be down-regulated for specific cell differentiation programmes.