Nonetheless, as also mentioned above, she is somewhat out of step with her own time precisely because of her unabashed endorsement of the need for hypotheses.
The French scientist Pierre Simon Laplace, when asked about God, told Napoleon, "I have no need of that hypothesis".
In the present study, we emphasize the need of using hypothesis-driven designs and conceptual models in impact assessment studies.
Transcriptomic analysis has emerged as a powerful tool to decipher cellular pathways that are modified following a gene expression alteration as it does not pre-require the need of restricting hypothesis.
The calculations indicated that the total sample size needed for hypotheses of interest approached the total number of cases from the completed and the then ongoing studies, approximately 15,000.
The emergence of complete genomes for many organisms, including humans, has created the need for hypotheses concerning the "function" of specific genes that encode specific proteins.
We agree with the recently advocated view of a need for hypothesis-based studies on specific pain-pain co-morbidities [ 50], but also on pain-dysfunction co-morbidities.
In the third example, we analyze the experimental data associated with the KNI and HB inhibitory cross regulation in Drosophila early development, described by the double graph of Figure 1, and we calibrate this model with the experimental data, without the need of a diffusion hypothesis for the zygotically produced proteins HB and KNI.
Additional research is needed for the testing of hypotheses involving effects of pet ownership with various health dimensions within population groups that are composed of different kinds of background characteristics.
Thus computational methods that make predictions are important to narrow the space of hypotheses that need to be tested experimentally.
