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A few CCDC6 somatic mutations have been reported in some tumours (http://www.sanger.ac.uk/genetics/CGP/cosmic), but they are still in need of characterization.
In the context of directed sequence finishing, low-copy repeats are often as in need of characterization as protein coding genes.
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We discuss the significance of these results in the context of a phased release of transgenic mosquitoes, and the need for characterization of local ecology prior to a release.
Hence, there is need of detailed characterization of lineaments and its validation for the groundwater potentiality and feeding.
While new materials with tailored properties appear every day, the need of appropriate characterization tools is still an important concern.
A recent population-based CNV study revealed the need of better characterization of CNVs, especially the small ones (<500 bp).We propose a three step computational framework (Identification of germline Changes in Copy Number or IgC2N) to discover and genotype germline CNVs.
The literature review revealed a number of arsenic exposure biomarkers in need of further characterization and validation.
The observed complex NCOs and distant forms of complex CO both point to a property of mammalian recombination that is poorly understood and in need of further characterization.
This paradoxical effect indicates that BRAF inhibitor treatment may be harmful in patients with small BRAF V600E-mutated subclones, underlining the need of accurate characterization of candidates for BRAF inhibitor treatment.
While the dataset used in this study was relatively small, the large number of observed novel allele sequence variants highlights the need for characterization of Y-STR alleles in larger sample populations.
The need for characterization of psoriasis lesion severity is clinically valuable and vital for dermatologists since it provides a reliable and precise decision on risk assessment.
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