In this context, the knowledge of the extent and the variations of under-reporting in different countries, as well as the variations in the related determinants in different countries, may assist not only in addressing the under-reporting problem globally, but also towards the adoption of a common European definition for injury severity, a need that is underlined in several studies.
The need for motivation and perseverance is underlined by Heather Finlay, director of Sainted, a PR business in the highly competitive music industry sector.
However, empirical research on the flipped classroom model in higher education, and more detailed investigations of students' perceptions of its use, is in its infancy and the need for further research is underlined by many (Bishop & Verleger, 2013; Uzunboylu & Karagozlu, 2015; Betihavas et al., 2015; Gilboy et al., 2015).
The need for diagnostic improvement is underlined by the finding that independent lung pathologists find only 41% agreement on LAC subclassification [ 3].
The need for such studies is underlined by preliminary data suggesting that strict metabolic control may reverse to some extent the consequence of diabetic cardiomyopathy [ 96].
The need for global action is underlined by recent evidence suggesting that the current Copenhagen Accord commitments will be insufficient to maintain a medium (50 66 %) chance of achieving the 2 °C target (den Elzen et al. 2011), and that it will be virtually impossible to compensate in later years if actions are delayed until 2030 (den Elzen et al. 2010).
Most likely, in TMB3500 cultures only the subpopulation readily adapted to the inhibitors at low pH were selected for, which is underlined by the need to apply thick inocula to provide a critical mass of this subpopulation.
The need to take urgent collective action is underlined even by the limited statistics available, which point to the scale and extent of violence.
The need for more trials in radiotherapy is underlined by the fact that this paradigm shift in attitude and assessment of benefit occurred when the results of the pivotal randomised trials were published in 1997 showing that postoperative radiotherapy could improve long-term overall survival and not just cause long-term morbidity.
