Nevertheless, these empirical and theoretical frameworks proposed need further validation.
Results of this study need further validation from larger study.
However, this novel approach will need further validation as it is not conform classic molecular manipulation.
Although the overall findings are consistent with recent studies, our thresholds do need further validation.
The findings present a sample of Iranian bicyclists and need further validation in other settings.
These results need further validation in carefully designed prospective studies to understand the long-term significance of RV dysfunction.
Furthermore, the definitions of LV systolic dysfunction and diastolic dysfunction need further validation in the sepsis population that could influence clinical outcomes [2, 28].
However, only nine patients were evaluable, only one of which did not respond to therapy and these results need further validation.
However, the model development is still work in progress to include the transportation sector into it and would need further validation especially concerning the economy sector.
This is balanced with a number of studies that present methodological developments in data collection and analysis methods that, while promising, need further validation.
Although a lot of functional imaging biomarkers have been proposed as pharmacodynamic biomarkers in early drug development, most of these biomarkers need further validation and standardization for their qualification in phase 1 and 2 human studies.
