Sentence examples for need for suppressive from inspiring English sources

The primary end-point was early failure defined as: 1) the need for unscheduled surgery, 2) death-related infection within the first 60 days after debridement or 3) the need for suppressive antibiotic treatment.

Several reports [ 21- 24] ascribe specific immune modulating and immune privileged features to hMSC, suggesting that these cells might serve as a universal off-the-shelf source of cells for use in regenerative medicine and can be transplanted into an allogeneic and xenogeneic host without the need for immune suppressive therapy.

More than 80% of patients undergoing ARS in the LOTUS trial reported control of heartburn and acid regurgitation at 5-year follow-up and this included no need for acid-suppressive medicine.

It is also possible that IL-2 changes the activation threshold needed for Treg suppressive capability at the cell-to-cell interaction level.

The initial treatment is based on amphotericin B and flucytosine; oral fluconazole is needed for chronic suppressive therapy, especially in AIDS patients.

TLR ligands also have a direct effect on Tregs, countering their suppressive properties without the need for dendritic cells.

There are precedents for suppressive actions of ZD7288 on other ion channels [33], [34].

Since suppressive function is a hallmark of Treg cells, we next tested for suppressive function of AIV-induced CD8+ Treg cells in vitro.

It has also been shown that patients with IBD display elevated levels of functionally suppressive HLA-DR− myeloid-derived cells, reflecting the need for immunosuppression in the state of disease.

All these considerations show that knowledge on the contribution of human MDSCs to the tumor immuno-suppressive network and tumor progression emphasizes the need for thorough MDSC monitoring in cancer patients, to correlate MDSC percentages with clinical outcomes.

In women on suppressive cART, the risk of viral rebound is increased following delivery, especially in the first 3 months, which may be related to reduced adherence, indicating the need for additional adherence support for postpartum women.