Sentence examples for need for receptor from inspiring English sources

Introduction of the c-myc epitope to the β chain allows capture of soluble D3 from the culture supernatant by immobilized anti-c-myc antibody, without the need for receptor purification.

We eliminated the need for receptor proteins or other signalling components because insufficient quantitative data are available to assess their contribution.

Because hSFs and hACs express IL-1Rrp2 mRNA, we hypothesized that these cells should be able to respond to IL-1F8 without need for receptor over-expression.

Overall, the ability of SMAL NPs to confer preferential specificity towards the cell surface domain could offer an exciting means of targeted delivery without the need for receptor-ligand-type strategies.

Without the need for receptors to recognise chemical messengers, gap junctions are much faster than chemical synapses at relaying signals.

Without the need for receptors to recognize chemical messengers, signaling at electrical synapses is more rapid than that which occurs across chemical synapses, the predominant kind of junctions between neurons.

To address the need for receptor-selective ligands, we decided to review the molecular evolution of the OT/AVP ligand receptor system to gain insight into the mechanism of receptor ligand recognition and binding.

Unlike most other enzymatically active toxins, which penetrate into cell cytosol from endosomes, several reports showed that the AC is delivered directly across the cytoplasmic membrane of cells without the need for receptor-mediated endocytosis of the toxin (Gentile et al., 1988; Gordon et al., 1988; Guermonprez et al., 1999; Schlecht et al., 2004; Basler et al., 2006;).

BS II is needed for receptor binding, whereas BS III is required for signaling [27 29].

In the case of CCR2, another protein, FROUNT, has recently been shown to bind to the receptor at the membrane and the authors demonstrated that FROUNT is needed for receptor clustering [10].

► Residues in the third extracellular loop and associated helices are needed for receptor expression; they may recognise RAMP1.