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This study yielded some general rules for designing an optimum composite shaft without any need for optimisation algorithms.
In a recent prospective observational study using thromboelastography (TEG) to evaluate anticoagulation profile during 32 VV ECMO episodes, heparin therapy and aPTT were associated with a reaction time of >90 min ("flat-line" profile); these results also emphasise the need for optimisation of anticoagulation management in this population [18].
To me, getting high was just a recreational practice without a need for optimisation, but the weed-hungry world disagrees and here we are, exploded faces, teenage highs and all.
This suggests the need for optimisation of the PFGE programme.
This variability clearly shows both the need for optimisation and for careful control of process conditions.
The 2013 ESHRE Guideline on management of women with endometriosis emphasizes the need for optimisation of management of women with endometriosis because there is a wide variety of clinical practice in the management of endometriosis, resulting in many women receiving delayed or suboptimal care [ 2].
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It has been widely believed that these patients need admission for "optimisation" prior to surgery, with days spent performing further investigations or initiating additional treatments by continually changing surgical and anaesthetic teams.
Consequently, there is a need for efficient optimisation procedures adapted to the FEM simulation.
The advantages of the framework over existing methods are that there is neither need for nonlinear optimisation nor need for spatial/modal models of the empty structure and the human-structure system.
The study highlights the need for detailed optimisation and financial analysis for large rainwater tanks to maximise the benefits.
A current drawback is the need for integrated optimisation methods, which include multiple physical-based simulation steps in an efficient way.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com