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Generally good agreement was found with some discrepancies indicating the need for further model improvement.
Current literature models for mass transfer underpredict laboratory autoclave reaction results, indicating a need for further model development, and in the interim requiring pilot-scale testing for scale-up purposes.
Yet, inspection of modification indices revealed several areas of localized strain, with multiple strong error covariances and cross-loadings, supporting the need for further model respecification.
In contrast, the within-city residuals for NO2 were less consistent with the measured values, stressing the need for further model refinement to take into account local geographic and emission characteristics.
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By using dimensionless variables formulated for this work, these charts permit the user to estimate the steady-state design variables described above for a wide range of configurations and conditions beyond those simulated without the need for further modeling.
To test the validity and robustness of our conclusions there is a need for further modeling (and, of course, field research) using alternative formulations for both natural and vaccine induced immunity.
Furthermore, whatever is found regarding the need for further modelling or experimentation, this kind of analysis also helps us gain some estimate of confidence in the answers currently provided by the model.
A population PKPD model for fibrinogen concentration time data based on the mechanisms apparent in the simplified model was developed and was able to describe the recovery of fibrinogen following brown snake envenomation without the need for further structural model development.
This sensitivity analysis provides a fast, albeit approximate, way to assess the robustness of inferences to the MAR assumption, avoiding the need for further imputation and model fitting to the imputed datasets.
The listed remaining challenges show the need for further development of models and instrumentation.
The results of this model assessment revealed the need for further development for stress strain models developed specifically for FRP-confined HSC or UHSC.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com