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Using simple counts relies on few underlying assumptions and alleviates the need for divergence data between lineages, which is required by the d N / d S approach described in the introduction.
Interestingly, variations in these three properties were interrelated in that divergence in one excludes the need for divergence in the other two but they are not directly predictive of each other.
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For example, it was revealed that the majority of the multigene P450 families in the model white rot fungus Phanerochaete chrysosporium appear to have expanded locally in its genome as a result of extensive gene duplications and rearrangements, indicating a strong need for functional divergence in response to environmental stimuli [ 23].
To most effectively use microsatellites for divergence estimation, we need to understand their mutation pattern and the factors that affect their mutation rate.
Monte Carlo simulations indicate that the number of generations needed for gene expression divergence to reach a given value, say 0.3 (human-orangutan), decreases rapidly and that the evolutionary rate of the previous model (L = 0.0) is generally larger than that of the refined model (L = 1.0).
In contrast to the successive divergences of the Nomascus species, the species radiation within Hylobates occurred over a much shorter time period of only 1.5 million years, thus explaining the need for larger datasets to resolve the divergences within the genus with significance.
These divergences emphasize the need for further experiments to get a better characterization of each T6SS components as well as defining the protein complexes building up the system.
The detection of partial overlap between intra-lineage and inter-lineage divergences suggests the need for combined analyses with nuclear genes and more detailed morphological/behavioural data to fully resolve species-level diversity and the biogeographic history of this group of murid rodents that may represent a species complex.
To obtain a stable and accurate scheme for surface curvature, a new reproducing divergence approximation without the need for a matrix inversion is derived.
The presence of rate variation can also suggest the need for more complex models in phylogenetics and divergence dating [see review by 28].
There's just not much room for divergence, if you read the whole Council".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com