The 20 clubs have accepted the need for boosting the number of academy products in first-team squads and are in talks over several options.
In some case where the rectified power is inadequate for the application, there is a need for boosting the output DC by stacking single rectifiers into series, forming the voltage multiplier [48].
Pharmacokinetic studies 46, 47 and dose-ranging trials 48, 49 suggest potential for once-daily dosing, low dose (50 mg) without the need for boosting, making dolutegravir a good candidate for a single-tablet regimen co-formulated pill.
Materials with new properties and improved functionalities are needed for boosting the performance and efficiency of the different types of devices, at a lower cost.
Except for deepening problems in the housing market, much of the American economy shows surprising strength and little need for a boost from cheaper loans.
For all of the major state pension programs in New Jersey, the study calculates either no need for any boost, or an increase of no more than 0.13percentt of 30-year tax income.
The EORTC randomized trial questioned the need for radiation boost to the post-tumorectomy surgical bed, with an evident age-related local control effect [ 2].
The $100 billion International Space Station may lose significant altitude, placing it in critical need for re-boosting by an amount potentially outside the range of typical Space Shuttle operations, which are in any case scheduled to end in 2010.
integrase inhibitor without the need for pharmacokinetic boosting that can be used effectively in combination with either TDF/FTC or ABC/3TC in a wide variety of HIV-positive individuals for first-line ART.
Dolutegravir has been designed for low-milligram daily dosing to achieve therapeutic concentrations and with a pharmacokinetic profile that enables once-daily administration without the need for pharmacokinetic boosting, so is a genuinely stand-alone once-daily drug.
