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Rather, the patient's history included chronic obstructive pulmonary disease, necrotizing pneumonia, bullous disease and coughing.
PVL is thought to be a key factor in the pathogenesis of necrotizing pneumonia.
This can be secondary to a ruptured bulla, cavitary neoplasm, necrotizing pneumonia, granulomatous infection/inflammation or post-thoracic intervention.
Hla is important in the pathogenesis of S. aureus necrotizing pneumonia [14] and dermonecrosis [21].
The mechanisms leading to death in necrotizing pneumonia also remain elusive.
The effects of gene deletion were also assessed in mouse models of necrotizing pneumonia and skin infection.
Hla is known to promote virulence in animal models of necrotizing pneumonia and skin infection [14], [21].
However, the relative contributions of agr and sae to the pathogenesis of necrotizing pneumonia caused by USA300 was not explored.
†Empyema, necrotizing pneumonia, pneumatocele, or pneumothorax.
S. aureus necrotizing pneumonia is similar pathologically to P. aeruginosa necrotizing pneumonia.
Animal models of necrotizing pneumonia provide conflicting results (37, 38 ).
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