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Biologically, this suggests that mutation of this gene is sufficient to promote tumorigenesis without the necessity to compromise mismatch repair activity, which is required for the development of dysplasia in approximately half of all CIMP colorectal cancers.
Similar(59)
Yet they understand the need to compromise, the necessity of cutting deals, in order to co-exist - especially in times of crisis.
But he explained his willingness to compromise as a necessity.
As a rule, however, the "peace" that Jesus spoke of was only open to minorities or to sects that practiced a rigorous ethics, while the Christian church itself had to compromise with worldly necessities.
But now, thanks to NTT DoCoMo, seniors won't have to compromise giving up necessities like a cellphone in exchange for not having to learn.
Since out-of-pocket health care payments account for a substantial share of household budget, they are likely to compromise the consumption of other basic necessities [ 20, 34].
We wanted to compromise.
We want to compromise.
Never really have to compromise.
Ivan was forced to compromise.
"Both parties need to compromise.
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