Sentence examples for necessity of sequence from inspiring English sources

But the dN/dS ratio for our samples was less than one on comparing them with reported subtype C and representative sequences of different clades, strongly emphasizing the necessity of sequence conservation at different disease stages and even across clades.

The extremely high-level sequence conservation found for this gene in this study may reflect the necessity of sequence conservation in maintaining the function of this gene.

This demonstrates the necessity of sequence overlap definitions and shows that the positions of reincluded taxa (indicated by asterisks in Figure 4 and Additional file 6) have to be discussed with caution.

These results point out for the necessity of sequencing RP1 when genetically investigating sporadic and arRCD.

Interestingly, a prevalence of ≈2.5% points out for the necessity of sequencing RP1 in sporadic and recessive cases of RCD.

It also argues for the necessity of sequencing additional primate species to gain a better and more comprehensive understanding of the human genome.

The necessity of sequencing heterozygous individuals, in combination with the relatively modest levels of genome coverage available with current technologies, required us to modify standard mutation detection software for our purposes.

The in silico sampling experiments demonstrate the necessity of high sequencing depth for increasing QTL detection in bulked segregant analysis.

On the other hand, whole shotgun sequencing of metagenomic DNA arguably provides a more robust and unbiased measurement of the taxonomic and functional content of a microbiome [ 7, 8], but its use has been limited due to the necessity of greater sequencing depth (higher cost) and significant computational challenges.

Thus, the multiplex PCR developed in this study using a minimum number of strategically designed primers provides a basis for rapid and simple differentiation of RSIVs from different hosts or countries merely by the observation of the predicted amplicons and without the necessity of making nucleotide sequence comparisons.

For instance, a key drawback to conventional methods of determining phage phylogeny is the necessity of whole genome sequence.