Exact(3)
The introduction of graphical analysis procedures for quantification of brain positron emission tomography (PET) data has made it possible to avoid many of the problems of regular compartmental modeling, such as the necessity of model identifiability and validation.
Whether or not, the error estimate is biased can thus only be detected with fresh data that are independent of the model selection process which shows the necessity of independent test data and thus the necessity of model assessment in the outer loop.
We also discussed the necessity of model adjustment by comparing with another simple adjustment method.
Similar(57)
This sets the necessity of modelling prostatic disorders to optimize a therapy against them.
The analysis of experimental data brings out clearly the importance of time dependent phenomenon like accumulation within the microphase and demonstrates the necessity of models based on unsteady state formulations for such cases.
Magnetization transfer experiments used to study in vivo cancer metabolism demonstrated the necessity of modeling bidirectional flux in an orthotopic tumor model.
A second major class of methods adopt a generative formalism to model the occurrences of motifs and CRMs as the output of some hidden stochastic processes, such as a first-order hidden Markov model (HMM), which removes the necessity of modeling the window size.
Ferrell asked "What is systems biology?" Lander can be said to ask rather "Why is systems biology?" - a question that he answers with an eloquent and absorbing disquisition on the absolute necessity of modelling, at all levels, if we wish to advance beyond knowledge to understanding.
The models differed in approach and age of dogs considered by necessity of the model, number of estimated parameters, or model reduction.
In the discussion, we briefly introduced our novel individual-based model comprising individual termites and their surroundings, and we addressed the necessity of this model in the functioning of the network and the formation of the network in relation to foraging behavior.
This leads to the necessity of structured models supporting process modeling.
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Justyna Jupowicz-Kozak
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