Sentence examples for necessity of administering from inspiring English sources

On the other hand, T790M point mutation arises after the patient's initial responses to EGFR TKI treatment, indicating the development of resistance to EGFR TKIs and the necessity of administering new-generation EGFR TKIs (e.g., AZD9291 and CO-1686).

The refusal to interfere with the judge is a way of acknowledging the necessity of impartially administering a social order.

The absence of the drill and the low level of necessity to administer local anesthesia have contributed to its acceptance.

The necessity for at least some cuts is increased by the fact that the costs of administering the welfare state, especially health and pensions, are set to rise extremely sharply in the decades ahead.

Furthermore, another recent study demonstrated the necessity to administer 50 and 60 mg/kg twice-daily daptomycin regimens for efficient therapy of experimental osteomyelitis in rabbits [ 42].

One of the predictors of non-compliance in patients with PD is the necessity for medication administered in multiple daily doses.

We prospectively examined the necessity of oral and parenteral fluoroquinolones administered to adult inpatients during a 6-week period in May and June 2009.

To study the necessity of data points-in-time, the mean absorbed dose for each kidney per administered activity (D/A administered) was determined when omitting one of the data points (1 h, 1 day, 2 days, or 7 days) and compared with D/A administered based on data from all time points.

28 Of note, treatment responders were more frequently administered daily oral corticosteroids and/or immunosuppressants compared with nonresponders, suggesting the necessity of long-term immunosuppression for sustained improvement.

To confirm the necessity of solTNF for PF development, a single low dose (200 ng/ml) of aerosolized recombinant human TNF (rhTNF) was administered to tnftm/tm mice immediately prior to BLM injection.

The union insists that the city should continue to administer the practical and written tests for a license and not de-emphasize the importance and necessity of having local experience.