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Dynamic hypothesis generation and confirmation techniques are a necessity for enabling scientific progress in extreme-scale science domains.
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This observation is consistent with the suggested necessity of Ser36 dephosphorylation, after interaction with Pin1, for enabling the proapoptotic function of p66Shc [ 24].
But he has since explained on live television that the receipts were a bookkeeping necessity that enabled him to use state money for secret diplomacy — for which there are no receipts.
Not because it's comforting, but because it's a necessity, it enables people to cope with the mourning process.
Increasing demands on the performance of intricate parts like bearings in biomedical and aerospace systems have created the necessity for tribological coatings that can enable systems to achieve enhanced performance in challenging environments.
In further investigations in vivo, we identified their unique role at multiple levels of the invasive cascade for SET cell and indicate the necessity for their functional balance to enable efficient invasion as well.
It is obvious that there will be a necessity for antibody reagents and quantitative methodologies to enable these studies.
This refined mechanism, exchanging single molecules within a macromolecular assembly, would enable isoform exchange without any necessity for demolition and reconstruction within the cell, and is expected to represent a principle, which may be exploited by other subcellular systems.
Thus SSWAP allows the encapsulation of data present in any database into an RDF/XML OWL graph for data transport, without the necessity for alterations to the underlying database structure or programming and while enabling a mechanism for semantic integration.
A careful numerical analysis is performed, which points out the numerical intricacies originating from the singularity of the nuclei and the necessity for approximations in the numerical setting, with the ambition to enable solutions within a predefined accuracy.
Also, if the global minimum is less well defined, faster refinement enables more cycles to be carried out, a necessity for good convergence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com