Sentence examples for necessitating high from inspiring English sources

Cardiogenic shock and multiple organ failure may further complicate the clinical course of some survivors, necessitating high dose inotropic drugs, vasopressors, renal replacement therapy, intra-aortic balloon pumps, mechanical assist devices or extra-corporeal membrane oxygenation [ 34, 35].

Systematic reviews summarise healthcare research evidence, and they are useful for assessing whether treatment benefits outweigh risks. 1 2 Accordingly, conclusions drawn from systematic reviews may impact clinical care and patient outcomes, thereby necessitating high standards of methodological rigour.

DAD patients primarily had oxygenation disturbances necessitating high plateau pressures and a chest X-ray with bilateral diffuse whitening, whereas SAD patients primarily had ventilation disturbances, with increased airway resistance and prolonged time constants and a chest X-ray with hyperinflation.

Economists at UBS said in a research note that the central bank's willingness to raise rates yet again also probably reflected a concern that strong commodity prices and investment activity would cause the overall economy to grow faster than currently projected, necessitating higher rates later.

In subconfluent cultures, with cells not touching each other, virions also fall between cells necessitating higher viral MOIs for efficient infection rates.

While MIRA can enrich DNA samples in the nanogram range [ 5], hybridization to the 2.1M NimbleGen microarray requires 1 μg of each DNA sample post-enrichment, necessitating high-magnitude whole genome amplification (WGA).

Firstly, ABPs are rapidly absorbed by the mineral surfaces of bone, thus necessitating high-dose regimens that are often associated with a range of complications including pyrexia, nephrotoxicity and electrolyte abnormalities [ 41].

Prone positioning may reduce chest wall compliance [ 35], potentially necessitating higher PEEP to offset these changes.

A decrease in ovarian response in patients with endometriomas necessitating higher gonadotropin doses has been described [ 12, 13].

Nevertheless, the increase in absconsions from secure units and accompanied privileges is a concern, given that these patients have been judged as being of higher risk to others and necessitating higher levels of supervision.

As described above, the target INR in bleeding patients was also lower than in the anticoagulation reversal patients, necessitating higher PCC doses in an attempt to achieve the lower target.