Sentence examples for necessitating development from inspiring English sources

Dye-NHS modification of streptavidin severely damaged ligand binding, necessitating development of a new streptavidin-retaining ultrastable binding after labeling.

Such rigorous procedures for quality control are costly and time-consuming, necessitating development of fast and inexpensive screening of live PSCs with high pluripotency prior to the rigorous quality control procedures.

While cutaneous delivery has great potential, the closest method used currently in the clinic – intradermal injection – is technically difficult, necessitating development of advanced targeting methods as reviewed in [8], [9].

Such predictive approach intrinsically limits the discovery of novel mechanistic links between chromatin configuration and gene expression as well as chromatin modifications, necessitating development of the alternative, more direct means to analyze genome-wide patterns of open and closed chromatin.

AS systems, when used as a method to identify new safety signals, often derive multiple potential links, necessitating development of algorithms that are informed by and integrated with clinical and scientific assessment to further prove causality; the SRS and other sources may be used to prespecify potential AEs of interest [ 15].

Many real life applications would, however, demand that the coupler point traces the path at specified velocity and acceleration, thus necessitating development of inverse velocity and acceleration analyses.

We then translate our Kokkos experiments in SNAP to PARTISN, necessitating engineering development, regression testing, and further thought.

Third, social networks of interest are very large, necessitating scalable tool development.

Health policy and systems researchers have a far broader, and potentially more transformative role in the system, necessitating autonomy in the development of ideas and in practice.

Acute respiratory distress syndrome had developed necessitating intensive care.

The objective response rates ranged from 21% to 33% with clinical benefit rate varying between 49% and 59% [ 1, 2, 4], necessitating improvements in treatments and development of response predictors to the different options.