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An increase in reactant temperature reduces the heat-sink effect necessitating a higher concentration of sand to extinguish the flame.
While low prices are certainly an attractive selling point, a variety of factors can bring pressure to bear on your bottom line, necessitating a higher charge for your services.
For instance, the presence of V433M polymorphism (rs2108622) in CYP4F2 (haplotype CYP4F2*3) caused elevated hepatic vitamin K1 levels, necessitating a higher warfarin dose to reach therapeutic anticoagulation response [ 20].
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A TCS may be required to reject a higher heat load to warm environments and a lower heat load to cold environments, necessitating a high turndown ratio, often on the order of 12 1.
Moreover, BACE1 inhibitors must be chronically administered, necessitating a high level of safety.
In addition, from a disease perspective it is important to know whether a gene involved in a respiratory process, for example, is expressed in the bronchi, the bronchioles or the alveoli, necessitating a high level of granularity in annotation.
This suggests that CaM-peptide may bind CaM at the site of interaction of W-5, but that CaM-peptide has a higher affinity necessitating a high concentration of W-5 (haloga log more than the IC50 of 210 µM) (20, 40) to inhibit binding of CaM-peptide to CaM.
This local atom rearrangement actively blunts the crack tip and necessitates a higher energy flux than the intrinsic material toughness upon the crack initiation.
The requirement of marking references, paired with the explicit instruction to cultivate a suspicious mode of critical reading, necessitated a higher attention to detail and textual engagement.
Put simply, convergence of its price level with the price level in more developed countries necessitates a higher rate of inflation.That's not much help explaining what happened in America and other rich economies in the 1970s.
This is particularly true in cancer treatments because cancer cells upregulate their expression of multidrug resistance transporters, which necessitates a higher concentration of extracellular drug to promote sufficiently high intracellular concentrations for cell killing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com