Sentence examples for necessitating a change of from inspiring English sources

Patients who took carbamazepine (16.7%) or topiramate (11.9%) had a higher incidence of adverse events, necessitating a change of treatment, compared with patients treated with valproate (4.3%), and fewer of them became seizure-free.

However, the superiority of CT over chest radiography has been documented in the literature; CT detects significant disease in patients with normal initial radiographs and in 20% will reveal more extensive injuries compared with the abnormal initial radiographs, necessitating a change of management [6].

After four cycles of treatment with paclitaxel and carboplatinum, she developed neuropathy necessitating a change of therapy and then proceeded to undergo doxorubicin and gemcitabine.

In some cases, night sweats can drench bedclothes and sheets, further disrupting sleep and necessitating a change of clothes and covers, which can also disturb the sleep of the individual's bed partner.

However, in some patients, functional impairment may not be sufficiently captured by functional measures, particularly in individuals with certain occupations who experience reduction in functioning and personal working capacity by involvement of a specific joint, necessitating a change of treatment even if otherwise in LDA.

Set mostly in London in the summer of 2002 it necessitated a change of style, he explains in his charming sing-song southern drawl one rain-sodden Vancouver afternoon.

"The Beginnings of a Complex...," her 1977 contribution to Documenta, was envisioned as a series of subterranean tunnels, but its floodprone site necessitated a change of plans.

A threatened strike by British Airways cabin staff necessitated a change of outward flights and of return carrier (thanks be to thee, O blessed Virgin).

In 1973 those forces gave Handel's Messiah at the BBC Proms, and six years later the growth in their activities necessitated a change of name to the City of London Sinfonia and City of London Sinfonia Chorus.

Sometimes a change that we make will necessitate a change of URL (Web address), causing bookmarks to fall out of synch.

The opening of the Pymble campus necessitated a change of name for the Croydon College, from The Presbyterian Ladies Collegee, Sydney to The Presbyterian Ladies Collegee, Croydon.