Sentence examples for necessitates validation from inspiring English sources

It is important to note that the small sample size, necessitates validation of these candidate gene expression changes in a larger cohort.

Molecular diagnostics have, in this respect, the advantage of being both sensitive and easy to integrate in laboratory practice, but the lack of morphological proof of a signal necessitates validation experiments.

Natural history studies necessitate validation of an automated, high-throughput method for HPV genomic DNA detection in oral rinse samples (ORS).

Subgroup analysis produced results using relatively small sample sizes; therefore, these findings necessitate validation on larger patient cohorts.

It necessitates further validation by the retrospective analysis of surgical series in terms of implant survival.

Consequently, the MAM process is poorly understood and build-process simulations are computationally demanding; this limits the availability of Design for Additive manufacturing (DFAM) tools, and necessitates experimental validation for commercial MAM applications.

Unfortunately, the poor aqueous solubility and high membrane binding affinity of hydrophobic drugs necessitates extensive validation of experimental methods to determine both liposome loading and permeability and thus the development of a quantitative understanding of the factors governing the encapsulation and retention/release of such compounds has been slow.

The vast diversity of cellular structures and intra- and extracellular metabolites necessitates the validation of metabolomic sampling protocols for different organisms.

This necessitates experimental validation of enhancer-gene interactions determined using prediction-based methods.

Our analysis revealed that some of the identified key signature genes have the potential to become early biomarker for obesity and diabetes, admittedly however, it necessitates further validation.

This potential and site-specific association and the observed predominance in PDD cannot be explained and necessitates further validation and investigation.