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Not surprisingly, the answer is complicated, and probably necessitates many more years of living in unfamiliar environments.
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The suspected convergence of care in protocol and usual care groups may have reduced the signal size and necessitated the study of many more than the planned number of patients.
Some of my other meetings left me with more ambiguous feelings: great age necessitates many sacrifices, the chiselling away of one's independence, the closing in of the world.
Many, many more.
Along with many, many more.
And more, many more places.
Many more needed help.
Many more.
My left eye became inflamed, slowing the healing process and necessitating many additional follow-up appointments.
The study necessitated many volunteer hours from participating school nurses.
Despite many studies on colorectal cancer, current therapeutic approaches cure only a fraction of patients [ 10, 21], which necessitates a more complete understanding of the kinds of mutations that contribute to tumorigenesis and their impact on tumor phenotypes.
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