Sentence examples for necessitates major from inspiring English sources

In addition, ceramic head fractures pose a serious complication which often necessitates major revision surgery.

Many executives assume that creating more cross-functional teams will necessitate major changes in organizational structure.

He twice injured the anterior cruciate ligament in his right knee, necessitating major surgery each time.

Were her eldest daughter's abdominal cysts, which necessitated major surgery, caused by the way she was conceived?

While auditing could still be done by private firms, our new approach would necessitate major changes in the way the audits are carried out.

This will necessitate major transformation of the way assessment operates in councils; certainly there has been growing recognition of the importance of the "universal offer" of information and advice that should be available to all, and that financial means testing should not precede needs assessment, but local practice remains highly variable.

And around that time, the tender heart he'd worn so many times on his shirtsleeves literally gave out on him, necessitating major cardiac surgery.

Grade 4 represents irreversible functional damage, necessitating major therapeutic intervention.

Of these patients, 3 (9%) even scored grade-4 toxicity on some of the parameters, denoting irreversible functional damage necessitating major therapeutic intervention.

10 Recent randomised controlled trials of non-drug related weight loss have highlighted the effectiveness of commercially run group programmes, which typically necessitate major input by participants (for example, one hour a week for 12 weeks).

The diversity of opinions concerning LUCA is in constant evolution and, new facts and ideas have been brought to attention in the last few years, These developments necessitate major adjustments in our approach; this is the subject of this paper.