There is a need for additional medical therapy and prevention of CRC, which necessitates further insight into the presently poorly understood mechanisms of colorectal mucosal defence, repair and carcinogenesis.
This new insight necessitates a more detailed examination of mammalian PRC1 complex function and targeting in vivo.
In patients suffering from acute psychosis, the lack of insight necessitates the use of 'informants', or third-parties who can contribute data on the patient's behavior and activities over the past week.
Toolis is especially good at exposing the kind of contradictory logic that living in a war zone and running an armed rebellion necessitates, and his insights about the difference between revolution and rebellion, as manifested in Northern Ireland, were key when it came to writing For the Good Times.
Understanding prion diseases necessitates detailed structural insights into PrPC and PrPSc.
Its incidence is rising, while it has developed resistance to the most widely used antifungal drugs, necessitating new approaches based on better insight into the biology of the organism.
That said, modeling 83 urban areas concurrently provides first-order insight about geographic areas necessitating further study, allowing for targeted future studies.
The discovery of wüstite (Fe1-xO) based catalyst is a key innovation for fused iron catalyst which necessitates the further research to obtain deeper insight into this novel catalyst.
However, the recent discovery that tau is modified by acetylation necessitates additional research to provide greater mechanistic insight into the spectrum of physiological consequences of tau acetylation, which may hold promise as a novel therapeutic target.
Meeker was among the first to argue that technology companies necessitated new, highly optimistic valuation methods, an insight that made her a celebrity.
This basic insight from the philosophy of language necessitates what this Article calls the "conversation" model of interpretation.
