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RNA targeting through small molecules is an emerging and promising therapeutic route that necessitates identification of small molecules that can selectively target specific RNA structures.
The case study takes its starting point in the perspective of an actor considering how to develop vehicle maintenance services for its customers and points at the need to enable understanding of the conditions for vehicle maintenance, which necessitates identification and analysis of the variety across transport service settings.
Accomplishment of a successful recruitment necessitates identification of the appropriate reef patch and a suitable microhabitat within this patch.
This necessitates identification of not only the function of individual proteins, but also to validate the physical interactions and biological processes in which they participate.
Global spread of MDR TB necessitates identification of treatment options with acceptable safety and tolerability for persons infected with drug-resistant strains.
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Further development and validation of the in silico approaches would necessitate identification of specific compounds and protocols required to establish the predictive power of the simulations to meet the standards of the requirements of regulators and industrial partners.
This necessitates the identification of aeroelastic parameters, known as flutter derivatives from wind tunnel experiments.
Nonetheless, the still growing application scope of DNA polymerases necessitates the identification of novel enzymes with tailor-made properties.
Extensive bone defects arising as a result of trauma, infection and tumour resection and other bone pathologies necessitates the identification of effective strategies in the form of tissue engineering, gene therapy and osteoinductive agents to enhance the bone repair process.
The confluence of forecasted urbanisation and projected heat wave increase necessitates the identification of strategies that both lower the overall health impact and narrow the gap in risk distribution within urban populations.
However, the scarcity of resources for, and the potential economic impact of, ameliorative actions that restore natural capital necessitates the identification of cost-effective geographic priorities, or hotspots, which provide multiple ecosystem goods and services.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com