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The low level of literacy might present problems in oral health promotion, which necessitates further development work to determine best delivery mode for health promotion There was a lack of restorative treatment, which could be due to prohibitively high cost, attitudes on the patients' part, or, prevailing attitude of dentists towards caries management.
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Difficulties with the initial deployment in early April of 2008 has necessitated further development work, with the second deployment planned for early November.
New understanding and new challenges to conservation biology might yet necessitate further development of the core set of SCP concepts.
Only an iterative cycle of improving genome annotation, structural and dynamic modelling and comparison of the predictions with experimental data will be successful, necessitating not only further development of computer-based annotation of gene functions and modelling algorithms but also the integration of whole metabolome profiling approaches.
Definition of the PfI2 role(s) during the life cycle necessitates further work, requiring the development of a powerful inducible expression system for P. falciparum.
Particularly, fungal chitin-linked asthma is increasing, but treatment options and successful clinical trials are scarce, necessitating further therapeutic developments.
Whereas solvent effects are taken into account implicitly in the ground- and excited-state wave functions, a proper treatment of dynamics, explicit solvent molecules, counterions, or even aggregation of the dyes in various networks is potentially required and would necessitate further methodological developments.
The known immunosuppressive effect of corticosteroid use coupled with the demonstrated role of immunosuppression in the development of sepsis following orthopedic trauma necessitates further studies examining this topic [17, 37, 52].
Further development of these diagnostic tests will necessitate understanding how the activities of well known genes are influenced by epistatic interactions within the pathogen species.
Research explicitly assessing the moderating role of intercultural influences in the development of PIU and psychopathology is still lacking and necessitates further investigations.
Further development and validation of the in silico approaches would necessitate identification of specific compounds and protocols required to establish the predictive power of the simulations to meet the standards of the requirements of regulators and industrial partners.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com