Therefore, our results necessitate confirmation by other, larger study groups.
The high prevalence of DFS70 autoantibodies in normal population, lack of association with a particular disease group and a general negative association with systemic and ANA associated autoimmune rheumatic diseases (SARD/AARD) necessitates the confirmation of DFS70 pattern.
Despite the relatively low false positive rate in the systematic screens performed thus far (5 7%) ([7], [8]), its presence necessitates the confirmation of the association of a RNAi phenotype with a particular gene by an independent method.
An initial rapid test was done and a reactive result necessitated a confirmation with Architect Abbot (IL, USA) Enzyme Linked Immuno-sorbent Assay (ELISA).
Another limitation is that the results of this preliminary study with small sample size necessitate further confirmation in large prospective studies and the functional relevance of the newly identified miRNAs needs to be further clarified.
The high sequence similarity necessitated further experimental confirmation.
To the best of our knowledge, one single study 19 evaluated 81 patients receiving 106 biventricular defibrillators for CRT, concluding that reuse of these devices is safe, without a raise in complication rate (infection, defibrillator malfunction), but necessitating further studies for validation and confirmation.
What I don't understand is why you feel that a confirmation of this fact would necessitate a publication or distribution of the mentioned document.
Furthermore, ANA testing by IIF is complicated by the number of positive patterns attainable (>50), which necessitates interpretation by a pathologist and requires appropriate confirmation tests.
Faxes are easily lost -- without so much as a trace; when important data are being transmitted, it necessitates hours of time-consuming follow-up and confirmation.
Although the resultant computational predictions should be interpreted cautiously prior to experimental confirmation, the rapid accumulation of information concerning sRNAs [ 24], necessitates computational, curated, relational databases of such entities in order to facilitate the construction of hypotheses aimed at defining their physiological mode of action.
