Working with screaming hot glass (2,250 degrees, to be exact — roughly three times hotter than a pizza oven) necessitates intense concentration; there is the very real danger of handling a molten material, but also a finite window of opportunity within which the glass is workable.
They ask the player to fully engage with their devious designs, with difficulty spikes that necessitate full concentration to overcome.
This is particularly true in cancer treatments because cancer cells upregulate their expression of multidrug resistance transporters, which necessitates a higher concentration of extracellular drug to promote sufficiently high intracellular concentrations for cell killing.
The establishment of the centrally planned economy and society required by socialist ideology necessitated an enormous concentration of power.
An increase in reactant temperature reduces the heat-sink effect necessitating a higher concentration of sand to extinguish the flame.
They ask the player to fully engage with their devious designs, with difficulty spikes that necessitate your full concentration.
This leads to unwanted side reactions which could lower the radiochemical yield (RCY) or necessitate a higher concentration of the precursor for the subsequent coupling reaction.
This suggests that CaM-peptide may bind CaM at the site of interaction of W-5, but that CaM-peptide has a higher affinity necessitating a high concentration of W-5 (haloga log more than the IC50 of 210 µM) (20, 40) to inhibit binding of CaM-peptide to CaM.
Because of the large difference of the IgG concentrations between serum and CSF, comparison of the avidity results necessitates independence of IgG concentration.
Additionally, at the clinical level, Duff et al. (1983) reported that suppression of ventricular arrhythmias in 40% of patients necessitates a plasma propranolol concentration in excess of that producing substantial β-receptor blockade.
This will stretch you out one more time before the end of your workout, in a pose necessitates great balance and concentration.
