While philosophers can create progress in their fields with nothing more than brain, pencil and paper, an objective understanding of complex natural and social systems necessitates more than can be achieved by any single person.
The IpTT necessitates little training and can be undertaken by those tasked with providing pressure relief care assistants and nurses giving them immediate feedback as to which patients require protection.
The design and analysis of the thermal/hydraulic systems in nuclear power plants necessitate system codes that can be used in the analysis of steady state and transient conditions.
On the other hand, when many are passive and few are active, there are mispricings, and when indexers have to trade, for instance around big dividends, corporate actions, index changes, seasonal cash flows, economic developments that necessitate cash flows, they can be exploited because they herd.
For example, certain health conditions will necessitate hospitalization, while others can be treated safely in the nursing home environment (depending on resources available at the nursing home).
When seated at a table with several people, the orienting movements necessitated by directional microphones can be very large, at times requiring the listener to turn up to 90° to either side.
This necessitates a data model that can be used to model any given problem instance in the form of a structured input language.
Regarding the effect of CDP-choline on leukocyte-endothel interactions and microcirculatory alterations in this study, no final conclusion can be drawn necessitating further studies.
Though considered the gold standard, RCTs are unable to answer all questions because it is not feasible and/or ethical to randomize patients to certain exposures, necessitating observational study designs that can be incorporated into systematic reviews to identify novel risk factors for disease outcomes.
Recently a second multi-targeting inhibitor has reported very preliminary evidence of activity, with responses reported in FGFR1 amplified cancers in the dose escalation study of E3810 [ 66] The multiple different mechanisms through which FGF signalling can be activated necessitate a complex approach to clinical development.
