Sentence examples for necessitates an alternative from inspiring English sources

These studies suggest an alternative Atlantic/Indian Ocean origin [ 8], which is inconsistent with an anti-tropical speciation event in the Pacific Ocean and necessitates an alternative explanation for the transition between oceans.

The cost and expertise required by certain preoperative tests, such as cardiopulmonary exercise testing, plus other limiting factors (e.g. dysmobility, acuity of surgery) necessitates an alternative approach to be developed for the objective assessment of perioperative risk in the substantial minority of patients who may sustain morbidity that impacts on their longer-term survival.

Protective ventilation in ARDS may lead to severe respiratory acidosis necessitating an alternative or additional approach.

Oedema may also render peripheral intravenous access technically impossible for patients under intensive care, necessitating an alternative route.

Currently metformin is considered the first line of defence, but many patients experience gastrointestinal adverse events, necessitating an alternative treatment approach.

For several Dex-responsive genes (Klf2, Klf4, Nfil3, Tiparp, Tgif1), however, treatment with Chx dramatically upregulated their basal expression, complicating the assessment of the relative contribution of direct vs. indirect effects of GR to their regulation (Additional file 3: Figure S2) and necessitating an alternative approach.

It argues that the rise of corporate intellectual property necessitates development of an alternative non-property regime to acknowledge and reward innovation by employees.

So, rapid development of infrastructure is likely to hinder sustainable development which necessitates development of an alternative material to reduce the demand for PC and decrease in CO2 emission.

The potential for myelosuppression or drug interactions may necessitate consideration of an alternative prophylactic agent.

Variables concerned with treatment effect modifiers will necessitate consideration of an alternative study design [ 7].

In southern Africa, for example, IRS with pyrethroid failed to control pyrethroid-resistant An. funestus and necessitated a switch to an alternative class of insecticide to which there was no resistance (6 ).