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The process of quantifying the number and magnitude of peaks due to each miRNA necessitates a threshold level to differentiate miRNAs of biological significance from background noise.
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Given the chronic nature of osteoarthritic pain, the presence of inflammation and well-established nociceptive pathways may necessitate a threshold dose or duration of treatment prior to clinical effect [ 41, 42].
In contrast to the semiquantitative nature of MSP, QMSP generates precise MI in continuous variables and thus necessitates that a threshold be set to dichotomise the data.
Namely, that even 100% bednet coverage is not necessarily sufficient to prevent malaria's persistence and that incorporating this imperfection of bednet coverage necessitates a stricter threshold of mosquito-killing efficacy to drive R0 below unity.
Re-annotation experiments would necessitate a higher threshold to avoid false positives, but experiments looking for novel junctions could use a lower threshold to include as many true positives as possible.
Seroma is not a rare side effect for energy-assisted liposuction, especially for high-volume treatment and may necessitate a lower threshold for closed drainage systems in selected patients.
Before this, naturally larger RR intervals may necessitate the use of a threshold value of greater than 6 ms in order to obtain physiologically relevant insight in the neonate mouse.
The inability to detect these qualitative and quantitative differences between sexes might be due to insufficient power from using a threshold model, necessitated by the extreme skewness of the raw data (Neale et al. 1994).
Existence of a threshold concentration for disease incidence, or a strongly nonlinear disease-to-intake response, would necessitate accurate determination of the shape of the population intake distribution.
There's a threshold.
It's a threshold question.
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