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All of these factors have necessitated the development of alternative analgesics4.
During World War II high-altitude bombing above the range of antiaircraft guns necessitated the development of rocket-powered weapons.
This has necessitated the development of a class of materials known as composites.
Growing interest in small-scale, portable energy devices has necessitated the development of micro-scale fuel processing systems.
The large size of BACs has necessitated the development of recombination-based methods to modify these DNAs.
The limited reparative capacity of the skin and inadequate conventional treatments has necessitated the development of skin substitutes.
These limitations have necessitated the development of newer anthracyclines whose structural and functional modifications circumvent these impediments.
In recent years, the emergence of multi-drug resistant strains of pathogenic microbes has necessitated the development of new therapeutic alternatives1.
The pace of deforestation worldwide has necessitated the development of strategies that restore forest cover quickly and efficiently.
This has necessitated the development of biofilm resistant coatings that are not detrimental to the quality of any measurement recorded.
For the contour method, the cylindrical geometry necessitated the development of a two-step process, and discontinuities across the unwelded portion of the joint required special treatment.
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